American Cruise Lines

The Ultimate American Adventure

Cruise historic waterways and awe-inspiring coastlines

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American Cruise Lines

American Cruise Lines

  • Brochure price $2,815 – Save up to 7%
    America

    4 Night Highlights of the Mississippi River

    America

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Houmas House Plantation, Louisiana
    • Baton Rouge, Louisiana
    • Oak Alley Plantation, Vacherie, Louisiana
    Sailing Dates:
    • March 2021
    • April 2021
    • June 2021
    • July 2021
    • November 2021
    interior from
    Not Available
    oceanview from
    $2,120
    $530pernight
    balcony from
    $2,615
    $654pernight
    suite from
    $3,560
    $890pernight
     
    interior from
    Not Available
  • Brochure price $3,200 – Save up to 6%
    American Pride

    4 Night Highlights of the Columbia River

    American Pride

    Departing from: Portland, Oregon
    Ports of Call:
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Stevenson, Washington
    Sailing Dates:
    • April 2021
    • June 2021
    interior from
    Not Available
    oceanview from
    $2,650
    $663pernight
    balcony from
    $3,000
    $750pernight
    suite from
    $4,445
    $1,111pernight
     
    interior from
    Not Available
  • Brochure price $5,600 – Save up to 7%
    America

    7 Night Lower Mississippi River

    America

    Departing from: Memphis, Tennessee
    Ports of Call:
    • River Cruising
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • Baton Rouge, Louisiana
    • Oak Alley Plantation, Vacherie, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • April 2021
    • May 2021
    interior from
    Not Available
    oceanview from
    $4,200
    $600pernight
    balcony from
    $5,200
    $743pernight
    suite from
    $7,095
    $1,014pernight
     
    interior from
    Not Available
  • Brochure price $4,915 – Save up to 8%
    America

    7 Night New Orleans

    America

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • St. Francisville, Louisiana
    • Baton Rouge, Louisiana
    • Houmas House Plantation, Louisiana
    Sailing Dates:
    • February 2021
    • March 2021
    • April 2021
    • June 2021
    • November 2021
    interior from
    Not Available
    oceanview from
    $3,645
    $521pernight
    balcony from
    $4,515
    $645pernight
    suite from
    $6,170
    $881pernight
     
    interior from
    Not Available
  • Brochure price $4,915 – Save up to 8%
    American Star
    4 rating out of 5  (1 reviews)

    7 Night Great Rivers of Florida

    American Star

    Departing from: Jacksonville, Florida
    Ports of Call:
    • Palatka, Florida
    • Green Cove Springs, Fl
    • St. Augustine, Florida
    • Amelia Island, Florida
    Sailing Dates:
    • March 2021
    • November 2021
    • December 2021
    interior from
    Not Available
    oceanview from
    $3,645
    $521pernight
    balcony from
    $4,515
    $645pernight
    suite from
    $6,170
    $881pernight
     
    interior from
    Not Available
    4 rating out of 5  (1 reviews)
  • Brochure price $5,255 – Save up to 8%
    Independence

    7 Night Historic South & Golden Isles

    Independence

    Departing from: Charleston, South Carolina
    Ports of Call:
    • Beaufort, South Carolina
    • Hilton Head Island, South Carolina
    • Savannah, Georgia
    • Cumberland Bay, South Georgia Island
    • Jekyll Island, Georgia
    • Amelia Island, Florida
    • Jacksonville, Florida
    Sailing Dates:
    • March 2021
    • April 2021
    interior from
    Not Available
    oceanview from
    $3,925
    $561pernight
    balcony from
    $4,855
    $694pernight
    suite from
    $6,635
    $948pernight
     
    interior from
    Not Available
  • Brochure price $5,600 – Save up to 7%
    Queen of the Mississippi

    7 Night Lower Mississippi River

    Queen of the Mississippi

    Departing from: Memphis, Tennessee
    Ports of Call:
    • River Cruising
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • Baton Rouge, Louisiana
    • Oak Alley Plantation, Vacherie, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • March 2021
    • April 2021
    • May 2021
    interior from
    Not Available
    oceanview from
    $4,200
    $600pernight
    balcony from
    $5,200
    $743pernight
    suite from
    $7,095
    $1,014pernight
     
    interior from
    Not Available
  • Brochure price $5,255 – Save up to 4%
    America

    7 Night Upper Mississippi River

    America

    Departing from: St. Louis, Missouri
    Ports of Call:
    • Hannibal, Missouri
    • Fort Madison, Iowa
    • Davenport, Iowa
    • Dubuque, Iowa
    • La Crosse, Wisconsin
    • Red Wing (Minneapolis), Minnesota
    • St. Paul, Minnesota
    Sailing Dates:
    • July 2021
    • August 2021
    • September 2021
    • October 2021
    interior from
    Not Available
    oceanview from
    $4,125
    $589pernight
    balcony from
    $5,055
    $722pernight
    suite from
    $6,835
    $976pernight
     
    interior from
    Not Available
  • Brochure price $4,045 – Save up to 5%
    Independence

    7 Night Mid Atlantic Inland Passage

    Independence

    Departing from: Charleston, South Carolina
    Ports of Call:
    • Wilmington, North Carolina
    • Beaufort, North Carolina
    • Kitty Hawk, North Carolina
    • Norfolk, Virginia
    • St. Michaels, Maryland
    • Baltimore, Maryland
    Sailing Dates:
    • May 2021
    interior from
    Not Available
    oceanview from
    $3,845
    $549pernight
    balcony from
    $4,715
    $674pernight
    suite from
    $6,370
    $910pernight
     
    interior from
    Not Available
  • Brochure price $5,255 – Save up to 8%
    American Spirit
    2 rating out of 5  (1 reviews)

    7 Night Puget Sound & San Juan Islands

    American Spirit

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Wa
    Sailing Dates:
    • April 2021
    • May 2021
    • June 2021
    • July 2021
    • August 2021
    • September 2021
    • October 2021
    interior from
    Not Available
    oceanview from
    $3,925
    $561pernight
    balcony from
    $4,855
    $694pernight
    suite from
    $6,635
    $948pernight
     
    interior from
    Not Available
    2 rating out of 5  (1 reviews)
  • Brochure price $5,940 – Save up to 3%
    Independence

    7 Night Maine Coast & Harbors

    Independence

    Departing from: Portland, Maine
    Ports of Call:
    • Bar Harbor, Maine
    • Castine, Maine
    • Camden, Maine
    • Rockland, Maine
    • Boothbay, Maine
    • Bath, Maine
    Sailing Dates:
    • June 2021
    • July 2021
    • August 2021
    • September 2021
    interior from
    Not Available
    oceanview from
    $4,680
    $669pernight
    balcony from
    $5,740
    $820pernight
    suite from
    $7,760
    $1,109pernight
     
    interior from
    Not Available
  • Brochure price $7,705 – Save up to 3%
    American Constitution

    10 Night American Revolution & Chesapeake Bay

    American Constitution

    Departing from: Baltimore, Maryland
    Ports of Call:
    • Norfolk, Virginia
    • Williamsburg, Virginia
    • Yorktown, Virginia
    • Washington, D.C. Usa
    • Mount Vernon, Virginia
    • River Cruising
    • Cambridge, Massachusetts
    • St. Michaels, Maryland
    • Annapolis, Maryland
    Sailing Dates:
    • April 2021
    interior from
    Not Available
    oceanview from
    $6,340
    $634pernight
    balcony from
    $7,505
    $751pernight
    suite from
    $9,305
    $931pernight
     
    interior from
    Not Available
  • Brochure price $7,235 – Save up to 3%
    America

    10 Night Mississippi River Gateway

    America

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Baton Rouge, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Memphis, Tennessee
    • New Madrid, Missouri
    • Paducah, Kentucky
    • St. Louis, Missouri
    Sailing Dates:
    • July 2021
    • August 2021
    interior from
    Not Available
    oceanview from
    $5,750
    $575pernight
    balcony from
    $7,035
    $704pernight
    suite from
    $9,435
    $944pernight
     
    interior from
    Not Available
  • Brochure price $7,670 – Save up to 3%
    American Song

    10 Night Northwest Pioneers Voyage

    American Song

    Departing from: Portland, Oregon
    Ports of Call:
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Stevenson, Washington
    • Hood River, Oregon
    • The Dalles, Oregon
    • Richland (Tri-Cities), Washington
    • Pendleton, Oregon
    • Clarkston, Washington
    Sailing Dates:
    • April 2021
    • July 2021
    • September 2021
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $7,470
    $747pernight
    suite from
    $10,475
    $1,048pernight
     
    interior from
    Not Available

See the U.S. Like Never Before Aboard American Cruise Lines

Explore the Sweet Land of Liberty Anew with River and Ocean Cruises Visiting 28 States

Set sail on the adventure of a lifetime aboard a small cruise ship or riverboat with ample amenities and top-notch service delivered by an all-American crew. A relaxed, casual atmosphere combined with an unparalleled attention to detail will make you feel right at home from the beginning to the end of your journey.

New England itineraries take you to charming seaside towns and islands, cruising the coast from Newport, Rhode Island up to Bar Harbor, Maine. Dive into the area's rich maritime history and taste some of the nation's best seafood along the way.

Across the country to the West Coast, you'll find American Cruise Lines river and ocean sailings to take you through the Pacific Northwest and Alaska. Set out on the very same trail that Lewis and Clark once traversed, see pods of orcas swimming in the Puget Sound, or sample delicious wines in wine country. Each itinerary offers so much to explore.

Sailing the Mississippi is a unique adventure all its own. With river cruises spanning St. Louis, Missouri to St. Paul, Minnesota and Memphis, Tennessee to New Orleans, Louisiana, there's so much to do and see. Visit old plantations and Civil War battlefields, tour the hometown of Mark Twain, and indulge in blues and BBQ.

Experience southern hospitality at its finest aboard Southeast cruises navigating the Intracoastal Waterway and Chesapeake Bay. Historic landmarks and local treasures abound from the great rivers of Florida to the Golden Isles and beyond.

With exceptional cuisine, daily entertainment, and complimentary experiences, traveling aboard an American Cruise Lines world-class ship is a remarkable experience you'll never forget. Book now to begin your next adventure of the United States.